Peer reviewed publications using the Way To Health platform

Innovative research and evidence based publications

Oct 2017

Effect of Financial Incentives on Glucose Monitoring Adherence and Glycemic Control Among Adolescents and Young Adults With Type 1 Diabetes

Charlene A. Wong, MD, MSHP; Victoria A. Miller, PhD; Kathryn Murphy, PhD; Dylan Small, PhD; Carol A. Ford, MD; Steven M. Willi, MD; Jordyn Feingold, MAPP; Alexander Morris, BS; Yoonhee P. Ha, MSc, MPhil; Jingsan Zhu, MS, MBA2; Wenli Wang, MS2; Mitesh S. Patel, MD, MBA, MS2

In a randomized clinical trial including 90 adolescents and young adults with poorly controlled type 1 diabetes, daily financial incentives improved glucose monitoring in the intervention group (50.0%) vs the control group (18.9%) but did not affect their glycemic control. Financial incentives showed promise for improving glucose monitoring behaviors among adolescents and young adults with type 1 diabetes

Jun 2017

Effect of Electronic Reminders, Financial Incentives, and Social Support on Outcomes After Myocardial Infarction: The HeartStrong Randomized Clinical Trial

Kevin G. Volpp, MD, PhD; Andrea B. Troxel, ScD6; Shivan J. Mehta, MD, MBA, MSHP; Laurie Norton, MA; Jingsan Zhu, MS, MBA; Raymond Lim, MA; Wenli Wang, MS; Noora Marcus, MA; Christian Terwiesch, PhD; Kristen Caldarella, MHA; Tova Levin, MBA; Mike Relish, MA; Nathan Negin, MD; Aaron Smith-McLallen, PhD; Richard Snyder, MD; Claire M. Spettell, PhD; Brian Drachman, MD; Daniel Kolansky, MD; David A. Asch, MD, MBA

In this randomized clinical trial of 1509 patients following acute myocardial infarction, there were no statistically significant differences between study arms in time to first rehospitalization for a vascular event or death, medication adherence, or cost.

Jun 2017

Time to selected quit date and subsequent rates of sustained smoking abstinence

George L. Anesi, Scott D. Halpern, Michael O. Harhay, Kevin G. Volpp, Kathryn Saulsgiver

In efforts to combat tobacco dependence, most smoking cessation programs offer individuals who smoke the choice of a target quit date. However, it is uncertain whether the time to the selected quit date is associated with participants’ chances of achieving sustained abstinence. In a pre-specified secondary analysis of a randomized clinical trial of four financial-incentive programs or usual care to encourage smoking cessation (Halpern et al. in N Engl J Med 372(22):2108–2117, doi:10.1056/NEJMoa1414293, 2015), study participants were instructed to select a quit date between 0 and 90 days from enrollment. Among those who selected a quit date and provided complete baseline data (n = 1848), we used multivariable logistic regression to evaluate the association of the time to the selected quit date with 6- and 12-month biochemically-confirmed abstinence rates. In the fully adjusted model, the probability of being abstinent at 6 months if the participant selected a quit date in weeks 1, 5, 10, and 13 were 39.6, 22.6, 10.9, and 4.3%, respectively.

Mar 2017

Patient and Partner Feedback Reports to Improve Statin Medication Adherence: A Randomized Control Trial

Ashok Reddy, Tiffany L. Huseman, Anne Canamucio, Steven C. Marcus, David A. AschK, evin Volpp, Judith A. Long

Simple nudges such as reminders and feedback reports to either a patient or a partner may facilitate improved medication adherence.

Mar 2017

Automated Reminders and Physician Notification to Promote Immunosuppression Adherence Among Kidney Transplant Recipients: A Randomized Trial

Peter P. Reese, MD, MSCE, Roy D. Bloom, MD, Jennifer Trofe-Clark, PharmD, Adam Mussell, MA, Daniel Leidy, BA, Simona Levsky, BS, Jingsan Zhu, MS, MBA, Lin Yang, MS, Wenli Wang, MS, Andrea Troxel, ScD, Harold I. Feldman, MD, MSCE, Kevin Volpp, MD, PhD

Provider notification and customized reminders appear promising in helping patients achieve better medication adherence, but these strategies require evaluation in trials powered to detect differences in clinical outcomes

Mar 2017

A Trial of Financial and Social Incentives to Increase Older Adults' Walking

Kristin A.HarkinsBA, Jeffrey T.Kullgren MD, MS, MPH; Scarlett L.Bellamy ScD; Jason Karlawish MD; Karen Glanz PhD, MPH

Incentive schemes that use donations to a charity of choice, personal financial incentives, or a combination of the two can each increase older adults’ initial uptake of increased levels of walking.

Dec 2016

Physician attitudes toward participating in a financial incentive program for LDL reduction are associated with patient outcomes

Tianyu Liu, David A.Asch, Kevin G.Volpp, Jingsan Zhu, Wenli Wang, Andrea B.Troxel, Aderinola Adejare, Darra D.Finnerty, Karen Hoffer, Judy A.Shea

In primary care practices, shared financial incentives for physicians and patients, but not incentives to physicians or patients alone, resulted in a statistically significant difference in reduction of LDL-C levels at 12 months. This reduction was modest, however, and further information is needed to understand whether this approach represents good value

Oct 2016

Participation Rates With Opt-out Enrollment in a Remote Monitoring Intervention for Patients With Myocardial Infarction

Shivan J. Mehta, MD, MBA, MSHP; Andrea B. Troxel, ScD; Noora Marcus, MA; Christina Jameson, BS; Devon Taylor, BS; David A. Asch, MD, MBA; Kevin G. Volpp, MD, PhD


Sep 2016

The design and conduct of Keep It Off - An online randomized trial of financial incentives for weight-loss maintenance

Pamela A Shaw, William S Yancy, Jr, Lisa Wesby, Victoria Ulrich, Andrea B Troxel, David Huffman, Gary D Foster, Kevin Volpp

Obesity continues to be a serious public health challenge. Rates are increasing worldwide, with nearly 70% of the US adults overweight or obese, leading to increased clinical and economic burden. While successful approaches for achieving weight loss have been identified, techniques for long-term maintenance of initial weight loss have largely been unsuccessful. Financial incentive interventions have been shown in several settings to be successful in motivating participants to adopt healthy behaviors.

Sep 2016

Rationale and design of a randomized trial of automated hovering for post-myocardial infarction patients: The HeartStrong program

Andrea B. Troxel, ScD; Andrea B. Troxel, ScD; Andrea B. Troxel, David A. Asch, MD, MBA, Shivan J. Mehta, MD, MBA, MSHP, Laurie Norton, MA, Devon Taylor, BS, Tirza A. Calderon, MPH, Raymond Lim, MA, Jingsan Zhu, MS, MBA, Daniel M. Kolansky, MD, Brian M. Drachman, MD, Kevin G. Volpp, MD, PhD

Coronary artery disease is the single leading cause of death in the United States, and medications can significantly reduce the rate of repeat cardiovascular events and treatment procedures. Adherence to these medications, however, is very low.