Vitality Smoking

Financial incentives, pharmacologic therapies, and electronic cigarettes (e-cigarettes) to promote smoking cessation

Scott D. Halpern, MD, PhD
Investigator
Kevin Volpp, MD, PhD
Investigator

Background

Whether financial incentives, pharmacologic therapies, and electronic cigarettes (e-cigarettes) promote smoking cessation among unselected smokers is unknown.

Intervention and Design

They randomly assigned smokers employed by 54 companies to one of four smoking-cessation interventions or to usual care. Usual care consisted of access to information regarding the benefits of smoking cessation and to a motivational text-messaging service.

Intervention - The four interventions consisted of usual care plus one of the following: free cessation aids (nicotine-replacement therapy or pharmacotherapy, with e-cigarettes if standard therapies failed); free e-cigarettes, without a requirement that standard therapies had been tried; free cessation aids plus $600 in rewards for sustained abstinence; or free cessation aids plus $600 in redeemable funds, deposited in a separate account for each participant, with money removed from the account if cessation milestones were not met.

Main Outcomes and Measures - The primary outcome was sustained smoking abstinence for 6 months after the target quit date. Secondary outcomes included the point prevalence for quitting at 1 month and sustained abstinence rates at 3 months and 12 months (i.e., 6 months after the end of the assigned intervention).

Way to Health Use

  • Study Enrollment: Enroll and randomize participants in the study

  • Financial Incentives: Provide participants with incentives for adherence

  • Cohorts: Created cohorts to analyze groups of participants with each other

Findings and Conclusions

Among 6131 smokers who were invited to enroll, 125 opted out and 6006 underwent randomization. Sustained abstinence rates through 6 months were 0.1% in the usual-care group, 0.5% in the free cessation aids group, 1.0% in the free e-cigarettes group, 2.0% in the rewards group, and 2.9% in the redeemable deposit group. With respect to sustained abstinence rates, redeemable deposits and rewards were superior to free cessation aids (P<0.001 and P=0.006, respectively, with significance levels adjusted for multiple comparisons). Redeemable deposits were superior to free e-cigarettes (P=0.008). Free e-cigarettes were not superior to usual care (P=0.20) or to free cessation aids (P=0.43). Among the 1191 employees (19.8%) who actively participated in the trial (the “engaged” cohort), sustained abstinence rates were four to six times as high as those among participants who did not actively engage in the trial, with similar relative effectiveness.

In this pragmatic trial of smoking cessation, financial incentives added to free cessation aids resulted in a higher rate of sustained smoking abstinence than free cessation aids alone. Among smokers who received usual care (information and motivational text messages), the addition of free cessation aids or e-cigarettes did not provide a benefit.

Publications


A Pragmatic Trial of E-Cigarettes, Incentives, and Drugs for Smoking Cessation